In vitro Tuberization and Colchicine Content Analysis of Gloriosa superba L.

Agrobacterium rhizogenes mediated hairy root induction for increased Colchicine content in Gloriosa superba L

Gloriosa superba L. a medicinally important monocot, member of the family Liliaceae, was investigated for callusing, direct regeneration and induction of hairy root using soil bacterium Agrobacterium rhizogenes. Friable callus was initiated from corms on basal MS medium amended with 2,4-D (1 mg L) and kinetin (1 mg L). Callus generated from such effective combinations were co-cultivated with th...

Colchicine cardiotoxicity following ingestion of Gloriosa superba tubers.

The clinical features of colchicine toxicity in a patient following ingestion of Gloriosa superba tubers are described. Gastroenteritis, acute renal failure, cardiotoxicity and haematological abnormalities were the main toxic manifestations. There was no hypotension and no neurological manifestations. Electrocardiographic changes were noteworthy and have not been reported previously.

Toxic encephalopathy due to colchicine--Gloriosa superba poisoning.

Gloriosa superba, a flowering plant widespread in South and Southeast Asia, is implicated in many cases of self-poisoning. Colchicine is concentrated in the seeds and tubers and this mediates its toxicity. We describe a 28-year-old woman who developed delayed encephalopathy after eating G superba tubers. MR scan of brain showed bilateral symmetrical T2 basal ganglia hyperintensities in the caud...

Acute fulminant hepatic failure due to colchicine – a rare manifestation of Gloriosa superba poisoning.

Phytochemical Screening of Gloriosa superba L. - from different Geographical Positions

Gloriosa superba Linn. is one of the important medicinal plant now in endangered list. This plant is widely used for several ethano-medicinal purposes by tribal peoples and traditional practitioners. Seeds and tubers contain valuale alkaloids viz., colchine and colchicoside as the major constituents, which are used an antidote for snake bites, gout and rheumatism. Present study was to evaluate ...